Including oxygen supplement in the early warning score: a prediction study comparing TOKS, modified TOKS and NEWS in a cohort of emergency patients

Abstract Background Early warning scores (EWS) are widely used in emergency departments and on general wards to detect critical illness and deterioration.TOKS (“Tidlig Opsporing af Kritisk Sygdom”) is an early warning score used in Central Denmark Region to monitor hospitalized patients.The objective of this study is to investigate whether incl

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Preparation of human primary macrophages to study the polarization from monocyte-derived macrophages to pro- or anti-inflammatory macrophages at biomaterial interface in vitro

Background/purpose: Testing of dental materials when in contact with innate immune cells has been so far hindered by the lack of proper in vitro models.Human primary monocyte-derived macrophages (MDMs) would be an excellent option to this aim.However, the inability to detach them from the tissue culture plates contrast the possibility to culture th

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